can hcv core ag testing replace the routine screening assays in patients on hemodialysis?
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Can HCV Core Ag Testing Replace the Routine Screening Assays in Patients on Hemodialysis?
We have recently read with great interest the article published in your most valuable journal entitled “Hepatitis C virus infection rate among seronegative hemodialysis patients screened by two methods: HCV core antigen and polymerase chain reaction” by Moini et al. (1). This study focused its message on determination of the prevalence of hepatitis C virus (HCV) infection in seronegative hemodi...
متن کاملThe Distributions of HCV Genotypes in Hemodialysis Patients in Iraq
Objectives: The aim of this report was to investigate the genotypes of HCV in patients on regular hemodialysis in Iraq Methods: A cross sectional study was conducted to investigate the genotypes of HCV in patients on regular hemodialysis in 7 centers across Iraq. 255 subjects with positive anti-HCV antibodies were recruited in this study. Results: To confirm the positivity, RTPCR was performe...
متن کاملUtility of HCV core antigen ELISA in the screening for hepatitis C virus infection in patients on hemodialysis.
An enzyme immuno assay for hepatitis C core antigen was recently developed and its performance was compared with that of the hepatitis C virus (HCV) RNA in the screening of HCV infection in patients on hemodialysis. One hundred and eleven chronic renal failure patients undergoing haemodialysis between May 2003 and October 2004 were included in the study. All the patients were tested for anti HC...
متن کاملHepatitis C virus (HCV) Infection Rate among Seronegative Hemodialysis Patients Screened by Two Methods; HCV Core Antigen and Polymerase Chain Reaction
BACKGROUND End-stage renal disease patients on chronic hemodialysis are among high risk groups for hepatitis C virus (HCV) infection for whom routine HCV screening is recommended. Anti-HCV antibody (ab) testing may not be reliable to detect all infected cases because of the blunted ab response due to depressed immune state in these patients. Using a more reliable, cost-effective and non-complex...
متن کاملhepatitis c virus (hcv) infection rate among seronegative hemodialysis patients screened by two methods; hcv core antigen and polymerase chain reaction
results among the 181 anti-hcv ab negative patients, 13 (7.2%) were positive for hcv core ag and 11 (6%) had detectable hcv rna with a range of 40-336543 iu/ml by pcr. the two tests had a high measurement agreement (kappa=0.82, p<0.001). of the 13 patients with positive hcv core ag test results, 3 were negative for hcv rna. considering real time pcr for hcv rna as the gold standard for hcv infe...
متن کاملAssociation of HCV Core Antigen Seropositivity with Long-Term Mortality in Patients on Regular Hemodialysis
Anti-hepatitis C virus (HCV) antibody seropositivity is independently associated with poor prognosis in hemodialysis (HD) patients. However, anti-HCV antibody cannot distinguish between patients with active infection and those who have recovered from infection. We therefore aimed in this study to examine the association of HCV core antigen (HCVcAg) seropositivity with mortality in HD patients. ...
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عنوان ژورنال:
hepatitis monthlyجلد ۱۴، شماره ۷، صفحات ۰-۰
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